07
Ten ounces of wild salmon a day for six months
Omega-3 index 4.9% to 10%, settling at 8.8% once I eased off.
worked
View experiment - Duration
- 180 days
- Markers
- Omega-3 index, hs-CRP
- Date
- Jun 2025 to Jun 2026
Nick Locascio · AI Entrepreneur & Founder
I build companies in AI and health.
I founded Rebody Health and co-founded Booth AI, backed by Y Combinator. My background includes a decade building machine learning systems and teaching deep learning at MIT. I also use AI to run my own health experiments.
Live stats · from the lab data——
Biomarkers tracked195
TSH · mIU/L5.91 0.56
Morning cortisol · ng/mL0.49 3.9
TPO antibodies · IU/mL900 571
Body fat % · DEXA21.7 17.3
Background
A decade building AI.
My work spans autonomous retail, generative AI, and deep learning research at MIT. I now run Rebody Health.
- NowRebody Health · Founder. Physician-led peptide and hormone care
- Co-foundedBooth AI · Y Combinator. Generative AI for ecommerce imagery
- PreviouslyDoorDash · Member of Technical Staff, Gen AI and Voice AI
- EngineeringStandard Cognition · Director of Engineering. Joined as employee #7 and helped scale to unicorn status. Led ML teams and shipped 10+ models for autonomous retail
- ConsultingSymantec · Deep Learning Consultant
- RecommendationsPinterest · ML Engineer
- iOSFitbit · Software Engineer
- ResearchMIT · Graduate Researcher
- TeachingMIT 6.S191 · Founded and taught Intro to Deep Learning, MIT's first deep learning course. Sponsored by Google Brain, NVIDIA, Amazon, and IBM Watson
- BookFundamentals of Deep Learning · Author. O'Reilly
- EMNLP 2016Neural Generation of Regular Expressions · First author
- Radiology 2017High-Risk Breast Lesions ML Model · Research publication
01. Latest experiments01
04
Cutting seven foods fixed my face swelling
Gluten, dairy, eggs, soy, corn, nightshades, alcohol. The bloat left in six weeks and has not come back.
worked
View experiment - Duration
- 90 days
- Markers
- Facial swelling (photo)
- Date
- Jun 2025
11
My lipid theory failed
LDL-P 2,284 to 1,243, then back to 2,230 a year later. The diet was not the lever I thought it was.
failed
View post-mortem - Duration
- 365 days
- Markers
- LDL-P, small LDL
- Date
- Jun 2026
02. Four things I make videos about
Four pillars. One body.
01Pillar
Hero Mode
When ambition costs you your health. The 4:30 a.m. wake-ups, the stimulants, the launch-week crashes, and what my labs said about it.
Read the story02Pillar
AI for Your Health
How I use Claude to research my labs and plan experiments. Get the prompts I use with my own health data.
Get the AI playbook03Pillar
Peptides Without the Hype
What I have actually used, what the data showed, and how to not get burned buying them.
Open the lab04Pillar
Visible Health & Longevity
Body composition, DEXA, face swelling, the half marathon. The results you can see, backed by the numbers you cannot.
Read the writing03. Writing
Long reads from the notebook.
- Evolution & MLFebruary 2026
Evolution Doesn’t Care About You
Category errors, fitness functions, and why your “broken” genes aren’t broken.
- Omega-3sJanuary 2026
Eating Like the Inuit
How I hit a 10% Omega-3 Index (top 5% globally) with 10oz of wild salmon daily and no supplements.
- Gut HealthFebruary 2026
My Gut Was Destroying Me From the Inside Out
How a Staphylococcus overgrowth at the 99.9th percentile was driving my autoimmune cascade, and the protocol that started reversing it.